Polynucleotides for the Under-Eye Area: How Many Treatments Are Needed and What Results Can You Expect?
The skin around the eyes is thin and delicate, so dehydration, fine lines and signs of fatigue often become visible early. Polynucleotide injections are intended to improve skin quality rather than alter facial features or create volume. They may be considered when the goal is a gradual improvement in elasticity, texture and overall skin appearance.
What are polynucleotides?
Polynucleotides are purified nucleotide chains used in aesthetic medicine as an injectable skin-quality treatment. They differ from botulinum toxin and traditional fillers: they do not immobilise muscles or provide substantial volume. Their purpose is to support skin repair processes and improve tissue quality. Clinical studies report improvements in periorbital wrinkles, texture and elasticity, although results vary with baseline skin condition, age and lifestyle.
What concerns may improve?
Treatment is commonly considered for dry, thin or tired-looking skin, fine expression lines, reduced elasticity and uneven texture. It may make the eye area look fresher. However, not every type of dark circle responds to injections. Pigmentation, visible vessels, tear-trough anatomy, puffiness and hereditary factors require different approaches. A consultation should identify the likely cause before treatment.
How many treatments are needed?
A common plan is a course of three sessions spaced approximately 2–4 weeks apart; some patients may require four. The exact schedule depends on the chosen product protocol and individual skin condition. Improvement is gradual, so the outcome should be assessed after the course rather than the next day. Maintenance can be discussed after several months.
Procedure and downtime
After consultation and contraindication screening, the skin is cleansed and topical anaesthesia may be used. The product is delivered through multiple small injections. Temporary papules, redness, tenderness, swelling or bruising may occur. Papules commonly settle within 1–3 days, while under-eye swelling can last longer in some people.
Aftercare
For the first 24 hours, avoid rubbing or massaging the area, applying makeup directly over injection sites and strenuous exercise. For several days, avoid saunas, steam rooms, swimming pools, very hot baths and intense sun exposure. Use daily sun protection and follow the personalised instructions provided by your practitioner.
Who should not have the treatment?
Treatment is generally avoided during pregnancy and breastfeeding, with active infection or inflammation in the area, or with a known allergy to product components. Autoimmune disease, bleeding disorders, anticoagulant use and a strong tendency to swelling require individual medical assessment and review of the specific product instructions.
Frequently asked questions
Do polynucleotides fill a tear trough?
No. Their primary purpose is to improve skin quality, not replace volume.
When will I see results?
Changes generally develop gradually over several weeks.
Is it painful?
Sensation varies; fine needles and topical anaesthesia may be used.
Can bruising occur?
Yes, bruising is possible with any injectable treatment.
Book a consultation
An individual consultation is needed to establish whether polynucleotides are the most appropriate option for your eye area. Book: elinabeauty.com/en/polynucleotides-pn-pdrn